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Two WALII researchers, Alejandra Arroyo (undergraduate student) and Sheila Ferer (research assistant) from the Tapia Lab at CSUCI, recently presented their work at The Allied Genetics Conference (TAGC) 2024 in Washington D.C.
Alejandra’s talk, “Drying Without Dying: Small Metabolites Counteract Proteotoxicity During Desiccation,” was a presentation on how trehalose can help organisms survive desiccation and the role trehalose may play in mitigating desiccation induced protein aggregation. Sheila presented a new method for studying how yeast cells modulate protein expression levels and localization throughout dehydration and rehydration in her talk called “Global proteome rewiring in times of desiccation and rehydration.” Sheila also discussed her plans for utilizing automated-microscopy and custom machine-learning algorithms in high-throughput experiments the Tapia lab plans to conduct to further characterize proteins/proteins families that change localization under desiccation conditions. In addition to their presentations at TAGC, Alejandra and Sheila were recently featured in a CSUCI News Release.
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Two graduate students from WALII labs, Kara Hunter (Sukenik Lab – UC Merced) and Jeff Lotthammer (Holehouse Lab – Washington University in St. Louis) have been awarded Student Research Achievement Awards (SRAA) for their poster presentations at the 2024 Biophysical Society meeting.
Beyond advancing our understanding of IDP functionality, their research may uncover novel targets and mechanisms to bolster desiccation resilience in yeast and other organisms.
ALBATROSS enables the instantaneous prediction of ensemble average properties at proteome-wide scale. ALBATROSS is lightweight, easy-to-use, and accessible as both a locally installable software package and a point-and-click style interface in the cloud. Jeff and his collaborators recently published a paper about ALBATROSS in Nature Methods.
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